5051 Nitschke Hall MS 303
2801 W. Bancroft St.
Toledo, OH 43606-3390
Phone: (419) 530-8030
Fax: (419) 530-8076
BIOE 4200: Biosystems and Control
(3 hours) Formulating, implementing and simulating mathematical models of biological and bioengineering systems. Linear and feedback control systems are emphasized; nonlinear models are introduced. Prerequisites: BIOE 4100; BIOE 4120.
BIOE 4350: Biomedical Optics
(3 hours) This course introduces the theory and design of optical biomedical instrumentation. Topics covered will include geometrical optics, electromagnetic theory, instrumentation, and optical principles applied to biomedical optics. Prerequisite: BIOE 3300.
BIOE 4610: Artificial Organs
(3 hours) The application of engineering principles to the design and analysis of artificial organs and their clinical application. Prerequisite: BIOE 3400.
BIOE 4620: Biochemical Engineering
(3 hours) The application of engineering principles to the design and analysis of biological processes that employ living organisms or biochemicals. Prerequisite: BIOE 3500.
BIOE 4630: Bioseparations
(3 hours) Practical and theoretical aspects of processes required to separate and purify cells, proteins and other biological compounds. Prerequisite: BIOE 3500.
BIOE 4640: Medical Imaging
(3 hours) An introduction to the physical principles, design and function of medical diagnostic imaging systems. Prerequisite: BIOE 3300.
BIOE 4670: Ultrasound Principles and Medical Applications
(3 hours) The basic principles and physics of ultrasound will be covered. Students will learn various medical applications of ultrasound and will be exposed to the latest developments in ultrasound technology. Prerequisite: MATH 3820 or 3860; PHYS 2140.
BIOE 4710: Biomechanics of Soft and Hard Tissues
(3 hours) Composite and hierarchical models of bones; models of bone remodeling. Soft tissues models: linear and nonlinear viscoelasticity, Fung's quasilinear viscoelastic theory. Biphasic and triphasic models and mechano-ionic interactions. Prerequisite: BIOE 3110.
BIOE 4720: Cellular Electrophysiology 
(3 hours) The physiology of electrically excitable tissues, including nerve, muscle and secretory tissues. Action potential generation, neurotransmission and modulatory mechanisms. Methods for constructing and using computational models of excitable membranes. Prerequisite: BIOE 4100; EECS 2300.
BIOE 4730: Computational Orthopedic Biomechanics
(3 hours) Introduction to and utilization of computational packages in orthopedic biomechanics. Computer aided design of implants, shape-optimization, finite element analysis of implants performance and failure of musculoskeletal organs, tissues and cells. Prerequisite: BIOE 1200; BIOE 3110.
BIOE 4740: Tissue Engineering
(3 hours) Application of principles from engineering and the life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function. Topics covered include: extracellular matrix materials; extracellular regulation of cell function; cell culture and cryopreservation; basic immunology and biocompatibility; specific tissue requirements; and progress in generating engineered substitutes. Prerequisite: BIOE 2200; BIOE 4100.
BIOE 4750: Experimental Methods in Orthopaedic Biomechanics
(3 hours) The theory and implementation of techniques used for the measurement of forces and motion within the musculoskeletal system at the system, organ and tissue levels. Prerequisite: BIOE 3110 or CIVE 1160.
BIOE 4810: Introduction to Nanotechnology
(3 hours) Introductory treatment of the theory and operation of physical electronic devices emphasizing electrical transport in metals, semiconductors and various models of BJTs, FETs, and MOSFETs and application to bioinstruments. Prerequisite: EECS 2300.
BIOE 4820: Nanotechnology and Microfabrication
(3 hours) A comprehensive treatment of the theory and techniques associated with Semiconductor nanotechnology and microfabrication of biomedical devices, sensors, MEMS and microsystems. Prerequisite: BIOE 3300.
BIOE 4910: Bioengineering Honors Thesis
(1 - 3 hours) Thesis research. The student completes and defends a written thesis under the direction and guidance of their faculty research advisor. Prerequisite: Senior standing in Bioengineering.
BIOE 4980: Bioengineering Special Topics
(1 - 3 hours) Selected subjects in the field of bioengineering with intensive investigation of the recent literature in a few areas of special interest to the class and the professor. Prerequisite: Consent of instructor.
BIOE 4990: Bioengineering Independent Study
(1 - 3 hours) The student, under the guidance of their research adviser, explores in-depth specific areas or topics related to their research. Prerequisite: Consent of instructor.